Description
What is Stilnox, and what are its effects and side effects?
Stilnox is a sleeping pill that is used for the short-term treatment of various forms of insomnia, heavy drowsiness, restlessness, and short-term sleep in patients 18 years of age and older. Stilnox 10 mg does not require a prescription to purchase. Its main active ingredient is Zolpidem hemitartrate 10 mg in 1 tablet. If this product does not meet your needs or interests, you may want to look at Provigil Modiodal Modafinil 200 mg. Please visit this link for further information on our Sleeping Disorders Pills
Stilnox: indications and use
Short-term medication for:
- various sleep disorders;
- acute insomnia;
- problems with sleep duration.
What are Stilnox’s effects?
The active ingredient has calming and stimulating effect on sleep by acting on special binding sites in the brain. Interaction with these binding sites enhances the effects of endogenous substances with relaxing and soporific effects.
The chemical active ingredient Zolpidem is a derivative of cyclopyrrolone. It interacts with the α and γ subunits of the GABA A receptor. This interaction with the GABA receptor results in enhanced GABA responses, which can be shown by electrophysiological techniques.
Stilnox Zolpidem gives these effects:
- sedative;
- hypnotic;
- anxiolytic;
- muscle relaxant;
- anticonvulsant.
Compared with benzodiazepines, Z-substances have less effect on sleep architecture, particularly on the phases of REM sleep.
Mechanism of drug absorption and elimination
Zolpidem is rapidly absorbed and has a rapid sedative effect in less than an hour. Bioavailability after oral administration is 70 percent. Zolpidem exhibits linear kinetics between therapeutic doses. Therapeutic levels in plasma range from 80 to 200 ng/ml. Maximum saturation in the blood occurs between 30 and 180 minutes.
The effect lasts for about 6 hours. It is excreted with urine and feces for about 2.5 hours on average.
The CR form allows a sufficient amount of the drug to persist on the receptors. This improves overall sleep time and prevents early morning awakening, which may be associated with the immediate-release form of zolpidem.
Stilnox: dosage
Adults take one film-coated tablet of Stilnox per day. This dosage should not be exceeded.
Elderly or infirm patients only receive half a film-coated tablet per day. This dosage should only be exceeded in exceptional cases – then no more than one film-coated tablet can be taken per day!
Patients with impaired liver function should not take more than half a tablet a day.
It should be taken with a small amount of liquid just before going to bed. The treatment should last only a few days. However, it may last up to two weeks and in some cases may last more than four weeks.
Stilnox: side effects
Common side effects: drowsiness, sleepiness the next day, headache, suppression of emotions, decreased alertness, confusion, dizziness, gastrointestinal disturbances, diarrhea, nausea, vomiting, visual disturbances, double vision, skin reactions, and memory loss.
Common side effects: fatigue, muscle weakness, unsteady gait, and unsteady movements.
Rare side effects: decreased libido.
Features:
In addition, psychological and “paradoxical” reactions such as restlessness, agitation, irritability, disinhibition, aggressiveness, abnormal thinking, psychosis, unusual behavior, alien extraversion, and other behavioral problems may occur. These reactions are called “paradoxical” because they are opposite to the desired effects of sedation and drowsiness.
As the effects wear off, insomnia may occur with associated reactions such as restlessness, mood changes, or anxiety.
An already existing depressive state can manifest itself for the first time or worsen. Use can lead to the development of physical and mental dependence.
Current U.S. studies suggest that effective concentrations of Zolpidem are still present in the blood of some patients the next morning, even when following the instructions for use. This is particularly true in female patients because they are slower to break down the active ingredient.
Thus, your ability to respond may be reduced the morning after taking Zolpidem. Do not drive or engage in other activities that require full concentration for at least eight hours after taking Zolpidem.
Inadmissibility of the use of
Stilnox Zolpidem should not be taken if you are hypersensitive to zolpidem. In addition, contraindications include severe hepatic dysfunction, sleep apnea syndrome, progressive muscle weakness, myasthenia gravis and severe respiratory failure.
Interactions
The following interactions should be considered when using Stilnox 10mg:
Alcohol: it is possible to increase the sedative effect of zolpidem, as well as the effect on the ability to drive vehicles and work with various mechanical devices.
In combination with other depressants, an increase in the central depressant effect is possible. Increased somnolence may be observed, and the following day – psychomotor disorders, including decreased ability to drive a car.
With antidepressants such as bupropion, desipramine, fluoxetine, sertraline, and venlafaxine, there may be a risk of visual deception.
Simultaneous use with narcotic analgesics may increase euphoria, which may accelerate the development of psychological dependence.
Pregnancy
Although teratogenic or embryotoxic effects have not been demonstrated in animal studies, safety in pregnancy in humans has not been established. Therefore, zolpidem is not recommended, especially in the first three months of pregnancy. If zolpidem is administered for a medical emergency in late pregnancy or during delivery, effects on the newborn such as hypothermia, hypotension and mild respiratory depression are expected based on pharmacological properties.
Breastfeeding
Although Zolpidem penetrates breast milk in insignificant amounts, it is recommended to avoid taking it, since studies on the effect on infants have not been conducted.
Where can you buy Stilnox online?
Stilnox 10 mg buy online you can in our online pharmacy, and our qualified pharmacists will be able to advise on possible interactions.
How long does Zolpidem stay in your system?
Zolpidem has a relatively short half-life, which means it stays in the body for a short period of time. The immediate-release form of Zolpidem has a half-life of about 2-3 hours, and the sustained-release form has a half-life of about 5 hours.
However, the time for which Zolpidem is completely eliminated from the body may vary depending on factors such as age, body weight, liver and kidney function, and the dosage and duration of the drug. Usually, Zolpidem is completely eliminated from the body within 24-48 hours after the last dose.
For effective treatment, the course of administration should not be interrupted. To have the medication at your fingertips at all times, comfortably order Zolpidem online.
What are the side effects of Zolpidem?
Common side effects of Zolpidem include drowsiness, dizziness, headache, nausea and dry mouth. Less common side effects include confusion, memory problems, mood changes, and visual disturbances.
Some people may also experience more serious side effects:
- Shortness of breath, slow breathing, or sleep apnea.
- Severe drowsiness or dizziness.
- Hypersensitivity to the medicine and allergic reactions such as hives, swelling of the throat or face, itching, and heart rhythm disturbances.
- Behavioral and psychological changes such as aggression, lethargy, hallucinations, decreased mood, suicidal thoughts or behavior.
- Decreased coordination of movements and impaired reactions.
If any serious side effects occur, you should see a doctor immediately.
Even if you decide to buy Zolpidem on line, you will have to get a prior consultation with your doctor.
It is important to take Zolpidem only under the supervision of a doctor and follow the instructions for use to avoid serious side effects and improve the effectiveness of the treatment.
Is Zolpidem addictive?
Zolpidem can be addictive, especially if used for a long period of time or in high doses.
People who take Zolpidem regularly may develop a tolerance to the drug, which can lead to dependence and withdrawal symptoms if they stop using it abruptly.
To avoid addiction, do not use the drug for longer than 2 weeks and do not exceed the maximum daily dose of 10-12.5 mg.
Can Zolpidem be used during pregnancy?
Zolpidem should only be used during pregnancy if the benefits outweigh the risks.
It is classified as a category C pregnancy medication, which means that animal studies have shown some adverse effects on the fetus, but adequate human studies have not been conducted.
For a safe pregnancy and fetal preservation, it is best to avoid taking Zolpidem generic. And replace it with a completely safe analog, with proven studies.
Can Zolpidem be used with other medications?
Zolpidem generic may interact with other medications, so it is important to tell your doctor about all medications you are taking. Include over-the-counter medications, herbs, and complementary foods to avoid unwanted side effects when using Zolpidem generic.
It may also interact with alcohol and other sleep-inducing substances, which may increase the risk of side effects.
Some of the medications that may interact with Zolpidem include:
- Central analgesics and narcotics such as morphine, codeine, oxycodone, etc.
- Antidepressants such as fluoxetine, sertraline, paroxetine, etc.
- Benzodiazepines such as diazepam, lorazepam, oxazepam, etc.
- Antihistamines such as diphenhydramine, cetirizine, loratadine, etc.
- Antiepileptic drugs such as carbamazepine, gabapentin, phenytoin, etc.
- Drugs to treat anxiety disorders, such as buspirone, etc.
- Anticonvulsants such as phenobarbital, clonazepam, lamotrigine, etc.
Is Zolpidem available without a prescription?
No, Zolpidem is not available without a prescription. It is a prescription drug available only with a prescription from a health care provider.
When you buy Zolpidem online, you also need to provide a prescription.
Can I use Zolpidem for long-term treatment of insomnia?
No, Zolpidem generic is not recommended for long-term use because it can be addictive and dependent. It is intended for short-term treatment of insomnia, usually no longer than two weeks.
The duration of the course is determined by the attending physician and depends on the individual characteristics of the body.
What should I do if I miss a dose of Zolpidem?
If you miss a dose of Zolpidem, take it as soon as you remember, but only if you still can’t sleep for at least 7-8 hours.
If this is close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed dose.
Treat responsibly, consult your doctor, and read the instructions carefully.
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